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Molecular Hydrogen protective against mild oxidative stress

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Molecular Hydrogen protective against mild oxidative stress ( molecular-hydrogen-protective-against-mild-oxidative-stress )

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Cognitive Vitality Reports® are reports written by neuroscientists at the Alzheimer’s Drug Discovery Foundation (ADDF). These scientific reports include analysis of drugs, drugs-in- development, drug targets, supplements, nutraceuticals, food/drink, non-pharmacologic interventions, and risk factors. Neuroscientists evaluate the potential benefit (or harm) for brain health, as well as for age-related health concerns that can affect brain health (e.g., cardiovascular diseases, cancers, diabetes/metabolic syndrome). In addition, these reports include evaluation of safety data, from clinical trials if available, and from preclinical models. Molecular Hydrogen Evidence Summary Hydrogen can protect against minor oxidative stress and inflammation-associated tissue damage, but cannot repair existing damage. Neuroprotective Benefit: No cognitive benefits were seen in a clinical trial of MCI patients. Hydrogen may be clinically useful to mitigate oxidative damage associated with mild brain trauma when administered close to time of injury, but cannot repair existing damage or reverse neuropathology. Aging and related health concerns: Hydrogen-rich water is protective against mild oxidative stress, has anti-inflammatory properties, and may regulate blood lipids and metabolism. May help protect the liver. Safety: Hydrogen therapy has a strong safety profile, but hydrogen is a very mild antioxidant and has a short half-life, so chronic treatment is likely needed for therapeutic benefit. 1

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