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KROMATON MODEL FCPC FAST CENTRIFUGAL PARTITIONING CHROMATOGRAPH OPERATING PRINCIPLE

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KROMATON MODEL FCPC FAST CENTRIFUGAL PARTITIONING CHROMATOGRAPH OPERATING PRINCIPLE ( kromaton-model-fcpc-fast-centrifugal-partitioning-chromatogr )

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703 West Housatonic Street – Ste L15 Pittsfield, Massachusetts 01201-6616 manufacturing centrifuges and centrifugal extraction equipment KROMATON MODEL FCPC FAST CENTRIFUGAL PARTITIONING CHROMATOGRAPH OPERATING PRINCIPLE The Kromaton centrifugal partitioning chromatograph functions based on the principles of liquid / liquid partitioning chromatography, in which two immiscible liquid phases are mixed together and then separated multiple times. The individual solutes are isolated based on the different partitioning coefficients of each compound in the solvent phase versus the diluent phase. Rotation Figure 1: Rotor diagram of FCPC centrifugal Figure 2: Individual disc from a Kromaton FCPC chromatograph rotor, showing individual extraction cells. The chromatograph’s rotor, shown in Figure 1, consists of several individual discs. An example of an individual disc is shown in Figure 2. There are seals between adjacent discs to isolate the cells from one disc to the other. The discs are aligned such that all of the cells are in series to create several hundred extraction stages. Each cell corresponds to a discrete extraction stage. OPERATION OF THE CENTRIFUGAL CHROMATOGRAPH: A stationary liquid phase is fed to the rotor while it is spinning at moderate rotational speed. The stationary phase is retained inside the rotor by the centrifugal force generated.

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KROMATON MODEL FCPC FAST CENTRIFUGAL PARTITIONING CHROMATOGRAPH OPERATING PRINCIPLE

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